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Mesothelioma and Asbestos

Asbestos, a mineral that occurs naturally in the form of long, thin fibers. Workers who are exposed to asbestos on a regular basis are at risk of developing mesothelioma as well as other lung diseases.

Symptoms of these diseases may not be evident for a long time after exposure to asbestos. Different types of asbestos can cause different symptoms.

Pleural Mesothelioma

Pleural mesothelioma is a type of cancer that occurs in the outer lung the lining (pleura). It is the most prevalent mesothelioma type and accounts for 70% to 79% all diagnosed cases. People with this condition experience pain in the chest and breathlessness, and they may feel the sensation of weight in the chest.

This type of cancer is usually caused through exposure to asbestos, which is a grouping of minerals comprised of microscopic fibres. The fibers, when inhaled can cause irritation and DNA mutations. The pleura covers the chest cavity and lungs, so these irritations can affect both the lungs and the heart of a person. Mesothelioma usually doesn't show symptoms until 30 to 50 year after exposure.

Chest pain and shortness breath are the most common symptoms. Patients may also feel tightness in their chest and coughing, or breathing difficulties. People who suffer from this cancer usually have previous exposure to asbestos in the workplace. Manufacturing, construction, and shipbuilding are the most common occupations which put people at risk chance of developing pleural mesothelioma. Individuals who have been in the military may be at an especially high risk due to the frequent asbestos use in Navy ships and army bunkers.

The most commonly used staging system for pleural mysothelioma has been the TNM (tumor, lymph nodes and metastases) staging system. The stage that a patient is in at the moment of diagnosis will determine the treatment plan they should follow. For instance, patients suffering from mesothelioma that is pleural in stage three or four have a poorer prognosis than patients with lower stages. Stage four mesothelioma is often spread to the liver, diaphragm or even the heart of a patient. This makes it more difficult to treat and increases the chance of complications for patients.

Peritoneal Mesothelioma

Contrary to pleural cancer that develops in the lung's lining it develops in the membrane that covers the abdominal cavity, including organs like the intestines and the liver. As with pleural mesothelioma exposure to asbestos is the cause of peritoneal msothelioma. There are only 300-500 cases diagnosed annually this is less than pleural asbestosis.

As with pleural asbestosis, symptoms can take a long time to manifest. Patients generally experience abdominal pain, and may have a mass in their abdomen. This mesothelioma type can cause nausea, weight loss, and fever. A lot of these symptoms can be misinterpreted as digestive issues and can lead to a misdiagnosis.

Generally, doctors can find mesothelioma by conducting an exhaustive medical history and physical exam. They can also use imaging tests like X-rays, CT scans and PET/CT scans to identify mesothelioma. These tests can reveal tumors and other symptoms of cancer that aren't visible on X-rays.

The results of these tests allow doctors to diagnose mesothelioma and determine the stage of the disease and suggest treatment options. The stage of the disease is determined based on the type of cells and whether or whether the tumor has spread to other areas of the body.

The most important risk factor for mesothelioma is exposure to asbestos. People who have been exposed to asbestos in jobs, such as electrical or plumbing work or in construction, manufacturing and manufacturing, are more likely to contract the disease. Even if someone is not employed in any of these areas however, they may be exposed to asbestos through family members or other sources. Anyone who suspects that they're at risk should talk to a doctor. A mesothelioma expert can help those who have a experience with asbestos to understand more about their risk.

Risk Factors

Asbestos is the primary risk factor for mesothelioma. It is responsible for up to the 80% of cases. Exposure to asbestos can occur due to work, military service or through living with a person who is exposed to asbestos or was previously exposed to doing so. Asbestos particles can be breathed in by people who are exposed to asbestos. The particles cause irritation to the linings, causing cancerous cells to form in the mesothelium. After exposure to asbestos mesothelioma can occur between 15 and 60 years.

Other risk factors include smoking, genetics and age. People in their 40s and 50s are more likely to develop mesothelioma than those who are younger or more senior. Mesothelioma can take between 20 and 60 years before it manifests cancer symptoms after the first exposure. It is also important to know that mesothelioma is a possibility in those who were exposed to asbestos, but did not engage directly with it. This is referred to as secondary or indirect asbestos exposure. It can be as hazardous as direct asbestos Legal exposure.

Smoking increases the chance of mesothelioma developing, as it damages the mesothelium. It also makes it more prone to. Mesothelioma can also be aggravated by certain illnesses, including asbestosis and pneumonia. Men are more likely to develop mesothelioma than females. This is because men are more likely to be exposed to asbestos and endure a an extended period of exposure than women. Men are also more likely to live with someone who had asbestos claim exposure and bring asbestos compensation fibers that have escaped home on their clothes. Women are less likely to come into exposure to asbestos and don't typically carry asbestos home on their clothes.

Diagnosis

Mesothelioma is a difficult disease to diagnose because the symptoms often resemble other conditions. This is why patients are sometimes wrongly diagnosed.

The first step in diagnosing mesothelioma is for NYU Langone doctors to perform an examination and write down a patient's medical history, including asbestos law exposure. Doctors will also recommend an CT scan or chest X-ray to look for lumps, abnormalities, and evidence of exposure to asbestos. These include plaques in the pleura, thickened pleura and calcium deposits.

Other diagnostic tests include an echocardiogram which examines the blood vessels and the heart and magnetic resonance imaging, also known as MRI, test that uses radio waves and magnets to create detailed images of the inside of the body. A surgical biopsy is yet another method doctors use to diagnose mesothelioma. In a surgical biopsy doctors take a small amount of tissue from the pleura or peritoneum for further analysis. A pathologist then examines the tissue with an magnifying glass to determine whether it contains cancerous cell.

The type of mesothelial cell involved and the benign or malignant nature of those cells as well as the location and stage of the tumor, are used to categorize the disease. Certain types of mesothelioma may be more likely to grow or spread, so it is important to get a definite diagnosis so doctors can treat the disease before it goes out of control.

Doctors can also perform tests in the laboratory on tumors in order to determine specific proteins, genes or other factors that will help them identify cancer characteristics and determine the best treatment. These results are known as staging.

Treatment

A mesothelioma diagnose can be terrifying. But, it is crucial to remember that the cancer is treatable, especially in its initial stages. Many patients with mesothelioma live with the disease for a long time without spreading.

Exposure to asbestos can trigger mesothelioma via a variety of mechanisms. Asbestos fibers, too small to detect or feel with the naked eye, can become airborne and cause irritation to the lung's lining (pleura). Over time the irritation can lead to the formation of scar tissue, which eventually lead to tumors.

The pleura is the area that surrounds the lungs and heart and the abdomen. Mesothelium consists of cells that respond when exposed to asbestos. They inflame the tissue and cause it to become scarred. As time passes, these changes cause the development of malignant mesothelioma cancers.

Breathing problems, chest discomfort or fluid buildup on the lungs are all signs of the pleural mesothelioma. In rare cases cancer can spread to the tissues surrounding the reproductive organs and heart.

If imaging scans reveal an underlying mass in the lungs or stomach doctors will recommend a biopsies. During the procedure, doctors remove small amounts of the tumor or fluid for lab tests. The results can confirm a mesothelioma diagnosis, and determine the best treatment option.

There are many types of treatment for mesothelioma such as chemotherapy and surgery. The majority of doctors employ combinations of these treatments. Participating in clinical trials for mesothelioma treatments may be beneficial to patients. Patients can learn more by consulting a mesothelioma expert who has treated the disease.

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